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The popularity of medical marijuana (also known as medical cannabis) continues to grow in the US. In 2018, over 3.5 million patients were registered to use medical cannabis; an increase from 2.6 million in March, 2016. As of January 2019, 33 states and Washington D.C., have laws legalizing medical marijuana. Ten states, Washington D.C., and Canada have legalized recreational marijuana. In addition, a growing number of states have laws specifically addressing the use of cannabidiol (CBD) for medical, as well as nonmedical, purposes.
The use of Cannabis sativa by the Chinese – for its strength as a fiber (in paper, bowstrings, rope, or clothing) and its medicinal properties – has been documented as far back as 4000 years ago. Hemp and marijuana are both plants in the Cannabis sativa family; however, they differ in structure and active ingredients. The most prevalent active ingredient in marijuana is tetrahydrocannabinol (THC), known for its psychoactive effects. Cannabidiol (CBD) is the second most prevalent active ingredient in marijuana (among many other pharmacologically active cannabinoids) and is the most prevalent active ingredient in hemp. Both THC and CBD have pharmacological effects. However, unlike THC, CBD does not have euphoric or intoxicating effects. A growing body of research suggests that CBD may be beneficial for a range of medical conditions including, but not limited to, anxiety, movement disorders, pain, sleep disorders, and seizure disorders. The FDA has approved CBD (Epidiolex®) for the treatment of 2 rare childhood-onset epilepsy syndromes. The evidence for CBD use in other conditions is sparse; it is derived mainly from animal, in vitro, and small human trials. However, because of its apparent lack of side effects in low to moderate doses, there is a great interest in CBD as a natural supplement...
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ACPE Universal Activity Number: 0428-0000-19-006-H01-P
Chief Editor and CE Administrator
Terry M. Baker, PharmD
Tracy Farnen, PharmD
James Chan, PharmD, PhD
Pharmacy Quality and Outcomes Coordinator
Associate Clinical Professor
Richard Ron Finley, B.S. Pharm.,R.Ph.
Consult Pharmacist Aging and Adult Health Services
Julio R. Lopez, PharmD, FCSHP
Adjunct Clinical Professor
Assistant Clinical Professor
Visiting Associate Professor and Lecturer
Pamela Mausner, MD
Helen Berlie, Pharm.D. CDE, BCACP
Ambulatory Care Specialist - Diabetes
Senior Editorial Advisor
Gerard Hatheway, PharmD, PhD
Belinda M. Danielson, RPh
Christopher M. DeSoto, PharmD
Angie S. Graham, PharmD
Cynthia Chan Huang, PharmD, MBA
Fred Plageman, PharmD
Editorial Advisor and Clinical Practice Consultant for Nurse Practitioners
Meuleman, RN, C, MS
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