New Drugs 2019
The number of new drugs approved each year has increased significantly since 1990. Various expedited approval pathways such as Orphan Drug Status designation, Accelerated Approval, Fast-Track, Priority Reviews, and the use of surrogate endpoints in studies have reduced the FDA review time from more than 3 years in 1983 to less than 1 year in 2017. In 2019, the FDA’s Center for Drug Evaluation and Research approved 48 novel drugs – a decline from 59 in 2018.. Read More »
Asthma Management: New Developments
Asthma is a chronic inflammatory disease that affects over 339 million individuals worldwide. Characterized by variable airflow limitation and bronchial hyperresponsiveness, symptoms include wheezing, shortness of breath, chest tightness, and/or cough. Asthma symptoms are episodic in nature, often worse at night or in the early morning, and can be triggered by factors such as exercise, airborne allergens, pollution, cigarette smoking, weather changes (eg, very cold, low humidity), and viral upper respiratory infections. To diagnose asthma, patients must have a history of variable respiratory symptoms, as well as limited expiratory airflow that has been confirmed with spirometry.. Read More »
Diabetes Management Update: A Patient-Centered Approach
According to the Centers for Disease Control (CDC), an estimated 30 million people in the US have diabetes (9% of the US population). Only 23 million have an official diagnosis, while 7 million are undiagnosed. The prevalence of diabetes is highest in American Indians/Alaskan Natives at 15%, followed by African Americans (13%), people of Hispanic ethnicity (12%) and Caucasians (7%).
An estimated 84 million people in the US have prediabetes (34% of the population) – including nearly half of adults aged 65 years old and older. The prevelance of diabetes is increasing... Read More »